A systematic and efficient approach for well calibration against wellhead pressure has been developed and verified for two reservoir simulators. The new approach integrates the producing well conditions into the flow table generation step so that the well productivity can be matched while generating the flow table. The main advantage of this approach is that most of the calibration effort is spent on individual wells, which requires less computational effort. Once the appropriate flow tables are generated, it only takes a few reservoir simulation runs to calibrate all the wells in the model. The computer applications based on this approach yield significant cost savings by reducing the project time from weeks to days, and by improving the quality of the well calibration.