Great attention has been paid recently to polymeric surfactants due to their structure. The incorporation of polymer and surfactant properties in one macromolecule offers significant advantages for chemical flooding. Aiming at high salinity and high temperature reservoirs, several polymeric surfactants were investigated for their potential in improving oil recovery. Experimental results demonstrated polymeric surfactants' good compatibility with field brines (both injection and produced brines). The interfacial tension (IFT) can be reduced by one order of magnitude compared to regular polymer solutions that have no surface activity. The emulsification can be significantly increased, too. The viscosity of the polymeric surfactants is much higher than regular surfactant solutions. With these unique properties, polymeric surfactants are considered a potential alternative to traditional surfactant-polymer formulations for chemical flooding in high salinity and high temperature reservoirs.