In the last 18 months, within the five Exploitation Integrated Assets in the South Region of PEMEX E&P, a well management program coupled with multidisciplinary teams has been implemented obtaining 24.5 MMSTB of oil and 40.1 Bscf of gas from workover of 372 wells that were shut in or had production problems. With the implementation and surveillance of this program in the field was possible for these assets to increase the production of oil to over 136 MSTB/D and gas to over 257 MMscf/D. These increases in production has made possible to maintain a production near to 500,000 STB/D of oil and 1,360 MMscf/D of gas in this region, offsetting natural production decline and loss of production due to a strong water invasion of wells. A profit-to-investment ratio of 16 has been obtained. Additional hydrocarbon production greater than 111 MSTB/D of oil and 196 MMscf/D of gas have been identified from 353 wells. The successful implementation of this program was based on the application of selected technologies that contributed to the increase of well productivity from the selected fields. This paper presents the applied methodology and the current results obtained from this well management program to optimize the recovery of hydrocarbons of the identified opportunities within these assets units with minimum investments. In addition to the value added of production increase through this well management approach, the following benefits were obtained: learning and applying the team work approach of well management, adaptation to a new cultural change of working as teams to solve difficult problems, training and transfer of diverse technologies, methodologies, and software technologies from the interdisciplinary teams to the technical personnel of PEMEX E&P, and specific well data information certified that can be used to evaluate reservoirs studies.