Hydrocarbon liquid consists of a range of components with different physico-chemistry characterization. Sometimes there are heavy component with crude oil such as asphaltene, naphthenic and paraffinic wax components and etc. Deposition of wax in both onshore and offshore pipelines presents a costly problem in the production and transportation of oil. There are several parameters contributing to wax deposition in multiphase crude oil flow, e.g. pressure drop, flow rate, pipe internal body surface roughness, surface energy of the pipe, liquid wetting of pipe wall as well as temperature difference between fluid and surroundings [1,2]. Application of internal coating of subsea pipelines can reduce wax deposition. The aim of the present work is to experimentally study the wax deposition in Malaysian waxy crude oil, where the data set studied was gathered from several experiments. Most of the methods can be used to remove the paraffinic wax deposition after it occurs. However, insulation systems yielded in better performance as it was found to help in the prevention of heat loss and solid deposition during flow conditionsThis study utilized flow loop apparatus. This paper compared the wax deposition behaviour with temperature, roughness and flow rate within the tested pipes [Polyvinyl Chloride (PVC), Ethylene - TetraFluoroEthylene (ETFE), and steel as a reference material]. Moreover, the prevention of temperature loss from liquid to surrounding and corrosion control significantly affects pressure drop across the pipeline . The conducted experiments concluded that ETFE had a better effect on the paraffin wax deposition control. Moreover, ETFE as a novel polymer based coating material was economically feasible to be utilized in the oil and gas downstream and upstream systems exposed to wax deposition.