The current evolution of hydrocarbon discoveries in the Nile Delta and Mediterranean put them as world class gas basin and encourage explorationists to do their best to identify and characterize the main structural elements which control the hydrocarbon accumulations. The study aimed to construct a regional structural setting for the pre-Messinian horizons and its impact on the different hydrocarbon types discovered in the study area. An integration of geological, geophysical and geochemical data has been done for mapping the structural elements for each horizon from Tortonian to Oligocene. The thermogenic gas and condensate discoveries in the relatively deeper Miocene reservoir (U, M &L Miocene) are related to the extensional fault system. While, the light oil discoveries were in the deepest reservoir belonging to Oilgocene & older sediments, which are attributed to deep-seated fault system (compressional & extensional deformations). The new plays in the deeper horizons for the future exploration will be attributed to the nature and timing of the structural elements and their relation to the hydrocarbon expulsion, migration and entrapment

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